The Most Experienced iPS Cell Team in the Nation

In July 2008, the Harvard Stem Cell Institute iPS Core Facility was created to accelerate research in the stem cell field by facilitating the derivation and distribution of induced pluripotent stem (iPS) cell lines. Disease-specific iPS cell lines provide us with an opportunity to study the mechanisms of disease and ultimately to develop new treatments.

In recent years, we have refined the iPS Core to better meet investigator needs. The iPS Core now operates on a fee-for-service basis to provide investigators with customized iPS derivation and genome editing based on the latest cutting-edge stem cell technologies.

  • We offer three non-integrating technologies (Sendai virus, miRNA and modified mRNA, and episomal vector) for reprogramming of a variety of somatic cell types.
  • In 2013, a new service was launched, offering the generation of genome engineered hESC or hiPS lines. We currently offer TALEN or CRISPR genome editing technologies to generate knock-out or knock-in lines for repair or introduction of mutations.
  • The iPS Core also serves as a repository for Harvard hESC lines and both control and disease-specific hiPS cell lines.

All of these services are available to the global research community.


December human cell culture training

October 14, 2014

Register now for the next iPS Core training workshop to be held December 4-5, 2014. The workshop, Human Pluripotent Stem Cell Culture: Feeder versus Feeder-free will be led by Laurence Daheron (HSCI iPS Core Facility) and Mark Fairey (Stem Cell Technologies). Learn more here.

iPS Core announces new rates

August 20, 2014

There are two new ways to save at the HSCI iPS core.


Derivation services (and ICC, EB formation, gene expression characterization) costs can now be reduced through a quantity discount for academic customers:

  • ¬†5-9 samples - 5% discount
  • 10-49 samples - 10% discount
  • 50 or more samples - 25% discount


HSCI and Harvard faculty can now enjoy reduced rates compared to other non-profit and for-profit institutions. For a complete list of prices, please see the core's derivation services and genome editing services, or contact Laurence Daheron.